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salubrinal  (Tocris)


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    Structured Review

    Tocris salubrinal
    Salubrinal, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 101 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/salubrinal+23-471-0/Salubrinal/10__1158_slash_0008___5472__can___24___3844-59-13-14
    Average 93 stars, based on 101 article reviews
    salubrinal - by Bioz Stars, 2026-09
    93/100 stars

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    Related Articles

    Activation Assay:

    Article Title: The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer
    Article Snippet: Human PBMCs (obtained from AllCells) were cultured in RPMI 1640 media supplemented with 10% FBS and 1% antibiotic-antimycotic (antianti, Invitrogen, 15240-062). .. For ISR pathway activation and inhibition, cells were treated with 100uM or 200uM Salubrinal (Tocris, 23-471-0) and/or 500-800nM ISRIB (Fisher Scientific, 5284) for 24h or 48h. .. For ISR activation, LUAD cells were treated with thapsigargin (5uM, Sigma, T9033), or with Arsenite (10-50uM), or grown in a hypoxic chamber for 24 or 48h.

    Article Title: Coordinated translational control of multiple immune checkpoints by the integrated stress response pathway in lung cancer
    Article Snippet: Human PBMCs (obtained from AllCells) were cultured in RPMI 1640 media supplemented with 10% FBS and 1% antibiotic-antimycotic (anti-anti, Invitrogen, 15240-062). .. For ISR pathway activation and inhibition, cells were treated with 100uM or 200uM Salubrinal (Tocris, 23-471-0) and/or 500-800nM ISRIB (Fisher Scientific, 5284) for 24h or 48h. .. For ISR activation, LUAD cells were treated with thapsigargin (5uM, Sigma, T9033), or with Arsenite (10-50uM), or grown in a hypoxic chamber for 24 or 48h.

    Inhibition:

    Article Title: The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer
    Article Snippet: Human PBMCs (obtained from AllCells) were cultured in RPMI 1640 media supplemented with 10% FBS and 1% antibiotic-antimycotic (antianti, Invitrogen, 15240-062). .. For ISR pathway activation and inhibition, cells were treated with 100uM or 200uM Salubrinal (Tocris, 23-471-0) and/or 500-800nM ISRIB (Fisher Scientific, 5284) for 24h or 48h. .. For ISR activation, LUAD cells were treated with thapsigargin (5uM, Sigma, T9033), or with Arsenite (10-50uM), or grown in a hypoxic chamber for 24 or 48h.

    Article Title: Coordinated translational control of multiple immune checkpoints by the integrated stress response pathway in lung cancer
    Article Snippet: Human PBMCs (obtained from AllCells) were cultured in RPMI 1640 media supplemented with 10% FBS and 1% antibiotic-antimycotic (anti-anti, Invitrogen, 15240-062). .. For ISR pathway activation and inhibition, cells were treated with 100uM or 200uM Salubrinal (Tocris, 23-471-0) and/or 500-800nM ISRIB (Fisher Scientific, 5284) for 24h or 48h. .. For ISR activation, LUAD cells were treated with thapsigargin (5uM, Sigma, T9033), or with Arsenite (10-50uM), or grown in a hypoxic chamber for 24 or 48h.



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